Thirty-eight years after a carnivorous, infectious plant called Rampage destroys earth, humans are in diaspora. Grizz Cortez, having a mysterious connection to the origin of Rampage, is the only human to survive an infection. She lives a solitary life on her ship, the Lolita Lebrón, managing her unique disability and evading detection by the Rampage Ministry. When a routine supply run ends with her finding that the galaxy's most notorious terrorist has stowed away on her ship, her life as she knows it is over.